The purpose of the study is to identify the peculiarities of chemical elements migration in the system "soil – soil-forming rocks" in the regional geo – systems of the North Caucasus with the one type biological cycle and heterogeneous soilforming rocks. As the regional geo – systems are high-altitude geo – botanical zones of high-mountain, mid-mountain and low-mountain physical and geographical sub domains landscape of the northern slopes of the greater Caucasus. Research methods: The object of study is the regional structure of chemical elements migration which are considered on the example of two high-altitude zones of Labino-Teberda landscape district allocated in the Western Caucasus within the Elbrus-Kazbek Alpine sub domain. To determine the intensity of chemical elements migration in the high-altitude zones, the coefficient of radial differentiation R, reflecting the genetic relationship of the soil with the soil-forming rock was used. The allocation of par genetic associations of chemical elements with the same regional structures of migration between the soil and heterogeneous soil-forming rocks within the boundaries of the high-altitude zones of the LabinoTeberdinsky district was performed by the cluster analysis. On the basis of the available data on high-altitude zones of all landscape districts of the mountainous, mid-mountainous and low-mountainous sub domains of the northern slopes of the greater Caucasus, a comparison of the regional structures of chemical elements migration was carried out. Research results: In geo – systems of the regional level with the same type of biological cycle and non-uniform soilforming rocks the regional structure of chemical elements migration are formed. They represent a certain sequence in changing the element migration intensity between the soil and heterogeneous rocks within the boundaries of the highaltitude zone. Different intensity of radial migration depends on the number of mobile and strongly bound compounds of the chemical elements. Their formation occurs in the rocks and soils during the long course of complex processes of rocks weathering and soil formation with a complex combination of factors of internal and external chemical elements migration. Conclusions. In geo – systems with the same type of biological cycle and heterogeneous soil-forming rocks within the physical and geographical sub domains of the northern slopes of the greater Caucasus, the peculiarities of regional structures formation of chemical elements migration have been developed. In the mountainous and mid-mountainous sub-regions, moving from the Western to the Eastern Caucasus during the formation of regional structures of chemical elements migration, the role of the biogenic factor is weakening and the influence of the lithogenic factor is increasing. All over the low mountains and foothill plains sub-regions (in the Western, Central and Eastern Caucasus), the biogenic factor is of primary importance for the majority of chemical elements in the formation of the regional migration structures.