In this study, vegetation coverage changes over a 30-year period for the Tuy Duc and Dak R’lap districts, Dak Nong province (central highland of Vietnam) were assessed using remote sensing and Geographic Information Systems (GIS) techniques. 03 Landsat satellite images, including Landsat TM February 13, 1990, Landsat TM February 22, 2005 and Landsat 8 January, 15 2020 were used to calculate the normalized difference vegetation index (NDVI), then assessed the changes in vegetation coverage density. The NDVI differencing method is also used as a change detection method and provides detailed information for monitoring changes in land cover in periods 1990 – 2005, 2005 – 2020 and 1990 – 2020. Analysis of the obtained results showed that the vegetation coverage declined sharply during 1990 – 2005 period, then the vegetation coverage has begun to recover in period 2005 – 2020. From the findings of this study, it can be easily concluded that the Tuy Duc and Dak R’lap areas has lost its valuable vegetation cover both qualitatively and quantitatively.